Current Methodologies for Membrane Permeability Assessment

Current Established Risk Assessment Methodologies and Tools

The technology behind information systems evolves at an exponential rate, while at the same time becoming more and more ubiquitous. This brings with it an implicit rise in the average complexity of systems as well as the number of external interactions. In order to allow a proper assessment of the security of such (sub)systems, a whole arsenal of methodologies, methods and tools have been devel...

High membrane permeability for melatonin

The pineal gland, an endocrine organ in the brain, synthesizes and secretes the circulating night hormone melatonin throughout the night. The literature states that this hormone is secreted by simple diffusion across the pinealocyte plasma membrane, but a direct quantitative measurement of membrane permeability has not been made. Experiments were designed to compare the cell membrane permeabili...

Erythrocyte Membrane Cation Permeability

A B S T R A C T Cetiedil has been reported to relieve painful crises in sickle cell anemia and to have antisickling properties in vitro. The drug alters neither oxygen affinity nor the solubility of deoxyhemoglobin S. Because the viscosity of the erythrocyte interior and the kinetics ofgelation are dependent on the concentration of hemoglobin, we postulated that cetiedil might inhibit sickling ...

Risk Assessment Methodologies for Soil Threats

Methodologies for Social Life Cycle Assessment*

Goal, Scope and Background. In recent years several different approaches towards Social Life Cycle Assessment (SLCA) have been developed. The purpose of this review is to compare these approaches in order to highlight methodological differences and general shortcomings. SLCA has several similarities with other social assessment tools, although, in order to limit the expanse of the review, only ...